| 2012 | Erase | The Chainsmokers featuring Priyanka Chopra | | 2 |
| 2013 | The Rookie | The Chainsmokers | | 1 |
| 2014 | #SELFIE | The Chainsmokers | 5 | 2 |
| 2014 | Kanye | The Chainsmokers ft. sirenXX | | 4 |
| 2014 | #SELFIE (instrumental mix) | The Chainsmokers | | 1 |
| 2015 | Let You Go | The Chainsmokers ft. Great Good Fine Ok | | 4 |
| 2015 | Good Intentions | The Chainsmokers ft. BullySongs | | 1 |
| 2015 | Roses | The Chainsmokers ft. ROZES | | 1 |
| 2015 | Waterbed | The Chainsmokers ft. Waterbed | | 1 |
| 2015 | Split (Only U) | Tiësto & The Chainsmokers | | 4 |
| 2015 | Until You Were Gone | The Chainsmokers & Tritonal ft. Emily Warren | | 2 |
| 2015 | New York City | The Chainsmokers, ROZES | | 2 |
| 2016 | Don’t Let Me Down | The Chainsmokers ft. Daya | | 1 |
| 2016 | Inside Out | The Chainsmokers ft. Charlee | | 1 |
| 2016 | Closer | The Chainsmokers ft. Halsey | 4.5 | 6 |
| 2016 | All We Know | The Chainsmokers ft. Phoebe Ryan | | 3 |
| 2016 | Setting Fires | The Chainsmokers ft. XYLØ | | 1 |
| 2017 | Paris | The Chainsmokers | | 1 |
| 2017 | Something Just Like This | The Chainsmokers & Coldplay | 3.35 | 2 |
| 2017 | The One | The Chainsmokers | | 2 |
| 2018 | Sick Boy | The Chainsmokers | 4 | 1 |
| 2018 | You Owe Me | The Chainsmokers | | 1 |
| 2018 | Everybody Hates Me | The Chainsmokers | | 1 |
| 2018 | Somebody | The Chainsmokers & Drew Love | | 1 |
| 2018 | Side Effects | The Chainsmokers feat. Emily Warren | | 1 |
| 2018 | Save Yourself | The Chainsmokers & NGHTMRE | | 1 |
| 2018 | This Feeling | The Chainsmokers feat. Kelsea Ballerini | | 1 |
| 2018 | Siren | The Chainsmokers & Aazar | | 1 |
| 2018 | Beach House | The Chainsmokers | | 1 |
| 2019 | Who Do You Love | The Chainsmokers ft. 5 Seconds of Summer | | 4 |
| 2019 | Kills You Slowly | The Chainsmokers | | 2 |
| 2019 | Do You Mean | The Chainsmokers ft. Ty Dolla $ign and bülow | | 2 |
| 2019 | Call You Mine | The Chainsmokers ft. Bebe Rexha | | 2 |
| 2019 | Takeaway | The Chainsmokers & ILLENIUM ft. Lennon Stella | 3 | 1 |
| 2019 | Push My Luck | The Chainsmokers | | 2 |
| 2022 | High | The Chainsmokers | | 1 |
| 2022 | iPad | The Chainsmokers | | 1 |
| 2022 | Riptide | The Chainsmokers | | 1 |
| 2022 | Why Can't You Wait (3LAU remix) | The Chainsmokers & Bob Moses | | 1 |
| 2022 | Wish on an Eyelash 2 | Mallrat & The Chainsmokers | | 1 |
| 2023 | Make Me Feel | The Chainsmokers & Cheyenne Giles | | 2 |
| 2023 | Up & Down | The Chainsmokers & 347aidan | | 1 |
| 2023 | Self Destruction Mode | The Chainsmokers & bludnymph | | 1 |
| 2023 | See You Again | The Chainsmokers, ILLENIUM & Carlie Hanson | | 1 |
| 2023 | Celular | Nicky Jam, The Chainsmokers & Maluma | 5 | 1 |
| 2023 | Summertime Friends | The Chainsmokers | | 1 |
| 2023 | Jungle | Alok, The Chainsmokers & Mae Stephens | | 2 |
| 2023 | fault in the stars | Powfu & The Chainsmokers | | 1 |
| 2023 | Live From Drew's Rental House | The Chainsmokers | | 1 |
| 2024 | Addicted | Zerb, The Chainsmokers & Ink | | 4 |
| 2024 | Friday | The Chainsmokers & Fridayy | | 1 |
| 2024 | Addicted (Summer version) | The Chainsmokers, Zerb & Ink | | 1 |
| 2024 | Addicted (ਆਦੀ) | The Chainsmokers, Zerb, Ink, Guru Randhawa & Jonita Gandhi | | 1 |
| 2024 | Don't Lie | The Chainsmokers feat. Kim Petras | | 1 |
| 2025 | Pink Pony Club (The Chainsmokers remix) | The Chainsmokers | | 1 |
| 2025 | White Wine & Adderall | The Chainsmokers & Beau Nox | | 2 |
| 2025 | Helium | The Chainsmokers & Anna Sofia | | 1 |
| 2025 | Spaces | BUNT., The Chainsmokers & Izzy Bizu | | 1 |
| 2025 | Smooth | The Chainsmokers | | 2 |
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